The Metabolic Syndrome in Clinical Practice


This book addresses the current issues about, and treatments for, the metabolic syndrome and its components, specifically obesity, diabetes, and cardiovascular disease. Cross-sectional surveys indicate that one third of adults and an alarming proportion of children in the United States have the metabolic syndrome, which also represents a global public health problem.
In 1988 Gerald Reaven first delivered his Banting lecture, “The Role of Insulin Resistance in Human Disease,” and the following year Harold Himsworth delivered the Goulstonian lecture, “Mechanisms of Diabetes,” to the Royal College of Physicians in London. Since then, an abundance of research has been conducted in the pathophysiology, epidemiology, and therapeutic strategies of the metabolic syndrome. Yet today there is no other topic in medicine that has provoked as much discussion as this syndrome; its precise cause has been debated, and even its very existence and usefulness has been challenged. These issues are addressed with sensitivity in this book. Whether it is called the metabolic syndrome (Scott Grundy), the insulin resistance syndrome (Reaven), or an “emperor without clothes” (Richard Kahn), it appears to be a simple syndrome in its clinical approach but it still remains a defiant problem. 

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