Inflammatory bowel disease research is changing.
Progress in defining and treating these diseases is advancing in lock step with the furious pace of technological
advances that continue to refine the tools of discovery.
With sequencing of the entire genome completed, genetics research is providing direction for molecular and immunological in vivo and in vitro investigation, which in
turn directs the development of targeted therapeutics. As
translational investigation evolves, what is learned in clinical research is combined with what is learned in basic sci-
ence research and is leading to a “personalized medicine”
approach for managing inflammatory bowel diseases and
is bringing the potential of prevention into view.
As Editors, our intention is that this book will provide
insight along the entire continuum from basic science to
clinical practice. The basic science chapters present findings in the context of what has already been established
about the clinicopathological nature of the diseases. The
clinical chapters describe the most effective applications of
all available diagnostic and therapeutic approaches. This
book reflects today’s trends toward globalism and is a
truly international effort. We encouraged our contributors
to editorialize and provide thought-provoking, progress-
stimulating content in their manuscripts. Now, more than
ever, is the combination of all disciplines working in con-
cert with the pharmaceutical industry key to the development of better treatments, with fewer side effects, and
for predicting patient responses. As drugs become more
specialized, it is vitally important to describe carefully patient populations both for study and for treatment. With
ever increasing evidence that the inflammatory bowel dis-
eases are heterogeneous disorders, drugs will likely only
be effective in certain subpopulations of patients.
Download here: Inflamatory Bowel Disease
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