A Clinical Trials Manual from the Duke Clincal Research Institute


In the nearly 10 years since we wrote the first edition of Lessons from a Horse Named Jim, we have seen a number of changes in our personal lives as well. Margaret (Maggie) had the opportunity to move with her family to Singapore and has lived there for the past 8 years. After returning to the clinical trials arena, Maggie has consulted with hospitals in the Singapore health care clusters to create a clinical research coordinator (CRC) network to facilitate CRC education and training that will support expanded trial work in that country. Kate has remained at the Duke Clinical Research Institute (DCRI), although her daily activities are removed from clinical site activities. However, when Kate is asked to offer insight into a site-related issue, that interaction still remains the most fulfilling aspect of her job. Through Maggie’s work in Singapore, she found herself often referring to the first edition of Jim and realized that the book could be strengthened by the addition of more in-depth information, while still fulfilling its purpose of serving as an intro- ductory manual for clinical research. In addition, Maggie felt that expanding information beyond North America would be worthwhile. Thus, work began on a second edition. 

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