Cornea and External Eye Disease


The second volume covers a broad range of conjunctival and corneal diseases, again with particular emphasis being placed on problem management.
Various new surgical approaches are currently being evaluated in the clinical setting, an example of which is posterior lamellar keratoplasty in Fuchs endothelial disease. While amniotic membrane transplantation has been in use for some years and for a range of indications, it is now becoming more and more popular for the treatment of ulceration in infectious keratitis. Tissue-engineered scaffolds as templates for corneal reconstruction are being investigated for possible future surgical approaches. Phototherapeutic keratectomy has been established for some years in the therapeutic repertoire for various phe- notypes of corneal dystrophy: this intervention is now safe and effective in many patients with superficial dystrophic corneal opacities or recur- rent erosion.
Molecular genetic evidence of corneal dystrophies is fascinating and has led to a completely new classification.
The chapter on corneal preservation shows the challenge for tissue banking behind the new surgical approaches. Inflammatory diseases of the cornea and conjunctiva remain a continuing challenge in every external eye disease clinic, described in the chapters on herpes simplex keratitis, ocular pemphigoid, adult inclusion conjunctivitis, and chronic blepharitis. Understanding of the biology of conjunctival melanoma is improving and confocal microscopy may become established as a new diagnostic aid and follow-up technique. 

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